South San Francisco Clinic
Part of San Mateo County Health
Contact & location
Address: 306 Spruce Ave, South San Francisco, CA 94080
Phone: 650-877-7070
Operating hours: about 40 hours per week — call for the daily schedule
County: San Mateo County
Website: co.sanmateo.ca.us
Treats everyone, insured or not — you do not need to be a US citizen. By law this federally funded health center serves all patients regardless of ability to pay, on a sliding-fee scale set by your income and family size. Call ahead to confirm hours, which services this site offers, and what to bring.
About this location
- Open year-round on a full-time schedule (HRSA site record).
- Part of the federal Health Center Program at this location since 1999.
About San Mateo County Health
San Mateo County Health reported caring for 4,975 patients across all its sites in 2025, and runs 20 locations listed in this directory.
- Insurance: 21% had no insurance, 65% had Medicaid or CHIP, 11% had Medicare, 2% had private insurance.
- 98% of patients with a known income earned at or below twice the federal poverty level (95% at or below it) — the range where sliding-fee discounts apply.
- Services patients received in 2025: medical care (3,775), dental care (1,054), mental health care (1,299), vision care (422), support services (case management, transport, enrollment help) (1,229).
- 45% of patients had limited English. If you prefer another language, ask for an interpreter when you call.
- Patients included 3,839 people experiencing homelessness, 1,448 agricultural workers and their families.
Source: HRSA Uniform Data System (UDS) 2025, as reported by San Mateo County Health for all of its sites combined — not specific to one address. Call to confirm what this location offers.
Other San Mateo County Health locations
Same organization and sliding-fee policy — useful if this site is closed, full, or doesn't offer the service you need.
- Daly City Youth Health Center — 2780 Junipero Serra Blvd, Daly City · 3.8 mi · 40 hrs/week
- Daly City Youth Health Center — 350 90th St FL 3RD, Daly City · 3.9 mi · 40 hrs/week
- Daly City Clinic — 380 90th St, Daly City · 4.0 mi · 40 hrs/week
- North County Mental Health — 375 89th St, Daly City · 4.0 mi · 40 hrs/week
- Central County Mental Health Ctr — 1950 Alameda DE las Pulgas, San Mateo · 9.3 mi · 40 hrs/week
- Health Services Agency Mental Health Division — 225 37th Ave, San Mateo · 11 mi · 40 hrs/week
Other health centers nearby
Run by different organizations, within 4 miles. All serve patients regardless of ability to pay.
- North East Medical Services - 200 Linden — South San Francisco, CA · 0.3 mi · North East Medical Services
- North East Medical Services - Sullivan Suite 150 — Daly City, CA · 3.6 mi · North East Medical Services
- North East Medical Services - Sullivan Suite 190 — Daly City, CA · 3.6 mi · North East Medical Services
- Hawkins Village Medical Clinic — San Francisco, CA · 3.6 mi · San Francisco Community Clinic Consortium
- North East Medical Services - Leland — San Francisco, CA · 3.9 mi · North East Medical Services
New here? What to bring · How the sliding-fee scale works
← All clinics in South San Francisco, CA
Listing sourced from the HRSA Health Center Program, refreshed 2026-10-05. Directory information only, not medical advice. Spotted a mistake? Use the feedback box below to let us know.
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